Adult-Stem Cell Based Products

Although there are myriad of Stem Cell oriented Patents and Protocols, the products I mention here are related to the work Of Henry E. Young. 

Specifically, the following two recent Patent Applications.

• USPA Number 20050255588  - Pluripotent embryonic-like stem cells, compositions, methods and uses thereof .  Young, Henry E.; (Macon, GA) ; Lucas, Paul A.; (Poughkeepsie, NY) - The present invention relates to pluripotent stem cells, particularly to pluripotent embryonic-like stem cells. The invention further relates to methods of purifying pluripotent embryonic-like stem cells and to compositions, cultures and clones thereof.

• USPA Number 20060183102 - Serum-free reagents for the isolation, cultivation, and cryopreservation of postnatal pluripotent epiblast-like stem cells. Young; Henry E.; (Macon, GA) ; Black; Calvin Asa JR.; (Macon, GA). -  Serum-free solutions suitable for use with postnatal pluripotent epiblast-like stem cells are disclosed. Methods of using serum-free solutions are also disclosed.

Young's Adult-derived stem cell preparations are straight forward and reliable.  They have different levels of abilities to differentiate.  Here I am discussing the most primitive, pluripotent epiblast-like stem cells

Epiblast Stem Cell (EBSC) advantages:

·        Renewable and inexhaustible consistent source of cells

·        EPSC’s can be cryo-stored indefinitely

·        The researcher can specify cell type

·        Cell production can be accurately scheduled

·        Genotyped cell source

·        Cell source is not immortalized by viral transformation

·        Cell source is not carcinoma

·        Cell source can be genetically modified to provide expression markers and toxicity response markers

·        Media utilized is Serum-Free using only human protein components making less regulatory issues.

I am also including data derived from my own personal observations.

BACKGROUND 

The most primitive stem cells are small, spherical, mostly, a nucleus with a little cytoplasm.  This cell morphology makes sense.  The primitive stem cell has little or no differentiation.  It is just an information packet with all kinds of potential. 

Also, the primitive stem cells sit all over the body waiting for a get started signal.  How else would the body replace and repair itself? 

All organs are composed of the four basic tissue types;

1. connective tissue,

2. epithelial tissue,

3. muscle tissues,

4. nerve tissue. 

A source for all cell types is thus needed.  So these most primitive adult-derived, epiblast-like stem cells have to be located in all sections of the body. 

COMMERCIAL SOURCES FOR ADULT-DERIVED STEM CELLS

For harvesting of adult stems cells, quantity and convenience should be the determining factors.  America is the land of adipose tissue.  FAT.  It is a reliable and relatively easy source of stem cells.  All Americans will be happy to donate there fat butts to their future health.       

POTENTIAL PRODUCTS

Click on the Product Buttons to see the specific work ups. 

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Last modified: 04/24/2008